CONTEXT: Emergence of coagulase‑negative staphylococci as pathogens in ophthalmia neonatorum. AIMS: To analyze the bacteriological spectrum of ophthalmia neonatorum and its associated risk factors. SETTINGS AND DESIGN: Retrospective analysis in a tertiary care hospital in India. SUBJECTS AND METHODS: A retrospective review was performed in a tertiary care center in India on 139 neonates presenting with conjunctivitis over a period of 3 years. All the neonates presenting to the out‑patient department, those admitted in the Neonatal Intensive care Unit and in‑patient wards were included in our study. The neonates were clinically examined and followed‑up by a single experienced ophthalmologist. Details including demographic data, age of the infant, type of delivery, investigations, and treatment outcomes were analyzed. STATISTICAL ANALYSIS USED: Frequency calculation using Microsoft Excel for windows 10. RESULTS: In the 92 samples with growth (66.2%), the most common organisms isolated were coagulase‑negative Staphylococci (35.9%), Klebsiella pneumoniae (16.3%), and Acinetobacter species (16.3%). Others were Staphylococcus aureus (14.1%), Pseudomonas aeruginosa (8.7%), and Escherichia coli (8.7%). Ophthalmia neonatorum was significantly higher in preterm infants born out of lower‑segment cesarean section and those requiring ventilatory support. CONCLUSIONS: Unlike gonococcus, which is implicated in ophthalmia neonatorum, our study shows varied microbiological spectrum and sensitivity patterns with coagulase‑negative staphylococci as the key pathogen. The role of coagulase‑negative staphylococci as a disease‑causing pathogen becomes increasingly important with an imperative need for prudent use of common antibiotics in treating these pathogenic bacteria.

CONTEXT: Emergence of coagulase‑negative staphylococci as pathogens in ophthalmia neonatorum. AIMS: To analyze the bacteriological spectrum of ophthalmia neonatorum and its associated risk factors. SETTINGS AND DESIGN: Retrospective analysis in a tertiary care hospital in India. SUBJECTS AND MET...