The survival of patients with systemic lupus erythematosus has increased over the last decade, which is associated with increased risk of morbidity. Osteoporosis remains one of leading morbidity associated with long term survivals. Multiple factors have been proposed to contribute to osteopenia, including limited physical activity, imited exposure to sunlight, duration of the disease activity, corticosteroid therapy, other immunosuppressant therapy, inadequate dietary intake of calcium and vitamins, and renal insufficiency. Children with Juvenile onset systemic lupus erythematosus (JSLE) are at even greater risk of developing osteopenia since the disease develops even before achieving their full potential peak bone mass.
The survival of patients with systemic lupus erythematosus has increased over the last decade, which is associated with increased risk of morbidity. Osteoporosis remains one of leading morbidity associated with long term survivals. Multiple factors have been proposed to contribute to osteopenia...
مادة فرعية
Pediatric Rheumatology