Systemic lupus erythematosus is an autoimmune disease with genetic and environmental components. In Oman, it is associated with early age of onset and aggressive presentation. A preliminary case-control study was conducted to identify potential risk factors associated with SLE development. Sixty Omani cases and sixty age- gender- and origin- matched controls participated by filling a questionnaire on demographic information, age of disease onset, family history and exposure to potential environmental factors. Results indicated that 25% of the participated cases have first-degree relatives with the disease (p=1e-4). Sun exposure found to be significantly associated with the disease (p=5e-4) and home incense smoke was suggested as a potential risk factor (p=3e-2). However, a larger size study is required to validate the preliminary findings and investigate the disease associated exposure durations and intensities.

Systemic lupus erythematosus is an autoimmune disease with genetic and environmental components. In Oman, it is associated with early age of onset and aggressive presentation. A preliminary case-control study was conducted to identify potential risk factors associated with SLE development. Sixt...