Background Chondrosarcomas are a rare tumor that has a variable biological characteristic. Also, their treatment clinically and surgically is controversial. Analyze the clinical statistics and prognostic factors of pelvic chondrosarcoma to provide a reference for clinical diagnosis and treatment. Method A total of 73 cases of chondrosarcoma were collected, including 24 pelvic from 2008 to 2017 hospital database and divided into 2 groups of pelvic chondrosarcoma and non-pelvic chondrosarcoma. The clinical characteristics and prognostic factors of pelvic chondrosarcoma were analyzed by different statistic methods. Result Among the 24 pelvic chondrosarcoma patients, the ratio of male to female was 1.4:1, and the median age was 43.5 years. According to the classification proposed by Enneking, there were 5 in area Ⅰ, 14 in area Ⅱ, and 5 in area Ⅲ; Histological grading of chondrosarcoma grade I in 1 case, Ⅱ in 15 cases, Ⅲ in 8 cases; The histological type was 17 conventional, 3 dedifferentiated, 2 secondary, myxoid 1 and mesenchymal 1. The overall survival rates were 3, 5 and 10 years (82.2±8.1) %, (77.3±8.9) %, (52.4±12.1) % respectively. The local recurrence rate of pelvic chondrosarcoma after surgical resection (83.3%) was significantly higher than that of other sites (34.7%), and the difference was statistically significant (P=0.000); The final proportion of amputation rate (50.0%) was also higher than other parts (20.4%) with a statistically significant difference (P=0.000). But the total survival of the 2 groups is (P=0.216). Conclusion Chondrosarcoma of bone generally has an excellent prognosis when optimal diagnosed and treated by an experienced team of specialists. But pelvic chondrosarcoma has a higher local recurrence rate than the other sites and is tend to result in amputation. Early local recurrence after surgery indicates a poor prognosis.

Background Chondrosarcomas are a rare tumor that has a variable biological characteristic. Also, their treatment clinically and surgically is controversial. Analyze the clinical statistics and prognostic factors of pelvic chondrosarcoma to provide a reference for clinical diagnosis and treatment. ...