Objectives: To assess the prevalence of fibroids complicating pregnancy among Omani women who followed-up and delivered at Sultan Qaboos University Hospital (SQUH) and to correlate the presence of large fibroids (>5cms) with maternal and neonatal outcomes. Methods: This retrospective cohort study was conducted at the Department of Obstetrics and Gynecology, SQUH from January 1, 2011 to December 31, 2016. Demographic data included maternal age, gravidity, parity, body mass index (BMI) and history of preterm delivery. Ultrasonographic data included total number of fibroids, number of fibroids > 5 cm in diameter and location. Main outcomes measured were preterm delivery, preterm premature rupture of membranes (PPROM), malpresentation, intrauterine growth restriction (IUGR), mode of delivery, postpartum hemorrhage, retained placenta, and cesarean myomectomy. Fetal outcomes included birth weight and APGAR score. Data was analyzed using SPSS version 22.. Chi-square test and t-test were used to calculate significant outcomes, p < 0.05 was considered statistically significant. Results: Total number of deliveries over the study period were 24 800. Among these, 62 women had fibroids complicating pregnancy giving an overall prevalence 0.25%. Of the 62 women with documented uterine fibroids, 41 had fibroids > 5 cm in diameter and formed the study group while the control group were 88 women with no fibroids and normal singleton pregnancies. The mean age, parity, BMI, and history of preterm delivery were comparable. Mean age of study group was 32.66 years. There was no statistically significant difference in obstetric outcomes in the study and control group in terms of preterm labor (p = 0.381), PPROM (p = 0.536), malpresentations (p=0.237), IUGR (p = 0.059), and retained placenta (p = 0.296). Postpartum hemorrhage was significantly higher in the study group (p = 0.018), the commonest cause being uterine atony (p = 0.007). Women with large fibroids had significantly increased cesarean section rate (p = 0.002), the main indications being obstructed labor and failure to progress (52.9%). Five of the 44 women in the study group (12.2%) underwent cesarean myomectomy. Regarding neonatal outcomes, a statistically significant difference was noted in the APGAR scores. Conclusions: Fibroids measuring > 5 cm in diameter are more likely to cause obstetric complications and are associated with higher cesarean rates. Pre-conception myomectomy is recommended for women with large fibroids.

Objectives: To assess the prevalence of fibroids complicating pregnancy among Omani women who followed-up and delivered at Sultan Qaboos University Hospital (SQUH) and to correlate the presence of large fibroids (>5cms) with maternal and neonatal outcomes. Methods: This retrospective cohort study w...