Objectives: The aim of this study was to analyze the characteristics of Covid-19 infected Health care workers (HCWs), and to measure their of immunoglobulin G (IgG) response. Methods: This is a retrospective and prospective cohort study where details of Covid-19 infected HCWs were collected in a pre-designed database. A single serum sample was collected from participating HCWs to detect the presence of (IgG) in their sera. Data were analyzed using SPSS statistical package. Results: Out of a total of 974 HCWs in Al-Nahdha Hospital, 103 (10.5%) were infected and tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by Real time reverse transcriptase polymerase chain reaction (RT-PCR). Nurses and doctors were the most affected groups. The source of infection was hospital in 50% of cases. Nurses were more than 4 times likely to have a hospital-acquired Covid-19 infection (OR: 4.63, 95% CI 1.711to12.523, p-value 0.002). HCWs working in Covid-19 areas were more likely to have hospital-acquired infection than community-acquired (p-value <0.005). All infected HCWs made a full recovery with only 4% requiring admission. Out of 74 tested HCWs for IgG, 60 (81%) were positive. IgG positivity rate was significantly higher among HCWs in Covid-19 areas (p-value 0.026) and among non-Omanis (p-value 0.008). Moreover, the median IgG level was significantly higher among non-Omanis (p-value 0.004). Conclusions: This study has highlighted the group at higher risk of hospital acquired Covid-19 infection which was the nurses and those working in Covid-19 areas. It highlighted as well, the high seropositivity among this infected group. These findings support the national guidelines on priority group for vaccination among HCWs which are those working in Covid-19 areas with no previous laboratory confirmed Covid-19.

Objectives: The aim of this study was to analyze the characteristics of Covid-19 infected Health care workers (HCWs), and to measure their of immunoglobulin G (IgG) response. Methods: This is a retrospective and prospective cohort study where details of Covid-19 infected HCWs were collected in a pre...