مقالة علمية
Effect of different polarities leaves crude extracts of Omani juniperus excels on antioxidant, antimicrobial and cytotoxic activities and their biochemical screening

Weli, Afaf M.


 

Effect of different polarities leaves crude extracts of Omani juniperus excels on antioxidant, antimicrobial and cytotoxic activities and their biochemical screening

Weli, Afaf M.

Objective: To prepare different polarities leave crude extracts of Juniperus excels (J. excels) and to determine their phytochemical screening, antioxidant, antimicrobial and cytotoxic activities. Methods: The phytochemical screening of different crude extracts was determined by wellestablished methods. The antioxidant activity was determined by free radical scavenging (2,2- diphenyl-1-picrylhydrazyl, DPPH) method. The antimicrobial activity was evaluated by agar disc diffusion method and cytotoxic activity was determined through brine shrimp lethality assay. Results: The phytochemical tests showed that alkaloids, flavonoids, saponins, steroide, triterpenoids and tannins are present in all leave crude extracts except chloroform crude extract do not contain tannins. The antioxidant results of crude extracts were found to be in the order of hydro alcoholic > chloroform> ethyl acetate >hexane. All leave crude extracts showed moderate antibacterial against gram positive and gram negative food borne pathogen bacteria. The cytotoxicity results revealed that hexane and chloroform extracts have killed all the shrimp larvae at the concentration of 500 毺g/mL. Conclusion: More in-vivo and in-vitro studies along with detailed phytochemical investigations are needed in order to potentially use this plant in the prevention and therapies of some oxidative damage related diseases.

Objective: To prepare different polarities leave crude extracts of Juniperus excels (J. excels) and to determine their phytochemical screening, antioxidant, antimicrobial and cytotoxic activities. Methods: The phytochemical screening of different crude extracts was determined by wellestablished me...

مادة فرعية

المؤلف : Weli, Afaf M.

مؤلف مشارك : Al Hinai, Jamila R.K
Al Mjrafi, Jawaher M.A
Alnaaimi, Jawaher R.S
Mohammad A. Hossain
Sadri Saeed
Md. S. Aktar

بيانات النشر : Asian Pacific Journal of Reproduction، 20 سبتمبر 2014مـ.

التصنيف الموضوعي : العلوم التطبيقية|العلوم الطبية .

المواضيع : Juniperus .

Antioxidant activities .

رقم الطبعة : 3

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