مقالة علمية
Clinical profile of myasthenia gravis in the Sultanate of Oman

Jacob, Poovathoor Chacko.


 

Clinical profile of myasthenia gravis in the Sultanate of Oman

Jacob, Poovathoor Chacko.

Objective: Clinical study and follow up of myasthenia gravis patients in Oman. Methods: Follow up of 50 consecutive myasthenia gravis patients referred to the Sultan Qaboos University Hospital, Oman for a median period of 3 years from 1997 to 2000. We based the diagnosis on the clinical picture, repetitive nerve stimulation tests and edrophonium test. We performed a computerized tomography scan of the chest and antiacetylcholine receptor antibodies. We reviewed the results of immuno modulatory treatment including thymectomy and compared these with other studies . Results: Of 50 patients, 6 had purely ocular myasthenia. Of the 44 with generalized myasthenia, 28 had bulbar involvement and 12 required ventilatory support. Eight out of 29 thymectomized patients had drug free remission after 2 years. There was worsening of myasthenic symptoms in only one out of 8 pregnancies and deliveries. Conclusions: Bulbar and ventilatory involvement are more common in our series as compared with western data. Pregnancy and delivery were well tolerated.

Objective: Clinical study and follow up of myasthenia gravis patients in Oman. Methods: Follow up of 50 consecutive myasthenia gravis patients referred to the Sultan Qaboos University Hospital, Oman for a median period of 3 years from 1997 to 2000. We based the diagnosis on the clinical picture...

مادة فرعية

المؤلف : Jacob, Poovathoor Chacko.

مؤلف مشارك : John T. Tharakan
Pratap R. Chand
Roshan L. Koul
Alexander P. Chacko

بيانات النشر : Saudi Arabia : Saudi Medical Journal، 2003مـ.

التصنيف الموضوعي : العلوم التطبيقية|العلوم الطبية .

المواضيع : Myasthenia gravis - Sultanate of Oman.

رقم الطبعة : 7

المصدر : Saudi Arabia.

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