مقالة علمية
Genotypes and allele frequencies of angiotensin converting enzyme (ACE) insertion/deletion polymorphism among Omanis = النوع الجيني الوراثي وتكرر الحليل (الاليل للإنزيم المحول للانجيوتنسين بأشكاله المختلفة في المواطنين العمانيين

Al Hinai, Ali T.


 

Genotypes and allele frequencies of angiotensin converting enzyme (ACE) insertion/deletion polymorphism among Omanis = النوع الجيني الوراثي وتكرر الحليل (الاليل للإنزيم المحول للانجيوتنسين بأشكاله المختلفة في المواطنين العمانيين

Al Hinai, Ali T.

ABSTRACT. Objective: To describe the angiotensin converting enzyme (ACE) genotype frequencies among Omani Arabs. Method: A polymerase chain reaction (PCR) test, based on separation of different size DNA fragments, was developed to test the presence or absence (polymorphism) of a small DNA deletion in the ACE gene. The subjects were 124 Omani Arab students of Sultan Qaboos University, Muscat. Results: The frequency of the I allele was 0.29, while that of the D allele was 0.71. The gene frequency distribution did not deviate from Hardy-Weinberg equilibrium. Conclusions: The frequency of D allele among Omanis is similar to that among other Arabs and Africans, but differs significantly from that among the Japanese and Chinese. Key Words: Allele, genotype, polymorphism, hypertension.

ABSTRACT. Objective: To describe the angiotensin converting enzyme (ACE) genotype frequencies among Omani Arabs. Method: A polymerase chain reaction (PCR) test, based on separation of different size DNA fragments, was developed to test the presence or absence (polymorphism) of a small DNA deletion ...

مادة فرعية

المؤلف : Al Hinai, Ali T.

مؤلف مشارك : Mohammed O Hassan

بيانات النشر : Muscat، Sultanat of Oman : Sultan Qaboos University / College of Medicine and Health Sciences، 2002مـ.

التصنيف الموضوعي : العلوم التطبيقية|العلوم الطبية .

المواضيع : Genetics .

الجينات الوراثية .

رقم الطبعة : 1

المصدر : Sultan Qaboos University / College of Medicine and Health Sciences : Muscat، Sulatante of Oman.

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