ورقة بحثية
تحديد المستوى المرجعي للأجسام المناعية المضادة (نوع G) للرشاشيات أسبيريغيلوس فوميغاتوس بين السكان البالغين العمانيين = Determination of an Aspergillus fumigatus-Specific Immunoglobulin G Reference Range in an Adult Omani Population

Al Rahman, Munira.


 

تحديد المستوى المرجعي للأجسام المناعية المضادة (نوع G) للرشاشيات أسبيريغيلوس فوميغاتوس بين السكان البالغين العمانيين = Determination of an Aspergillus fumigatus-Specific Immunoglobulin G Reference Range in an Adult Omani Population

Al Rahman, Munira.

Objectives: The presence of abnormally high levels of Aspergillus fumigatus-specific immunoglobulin (Ig) G antibodies can serve as a diagnostic criterion for severe conditions like allergic bronchopulmonary and chronic pulmonary aspergillosis. This study aimed to determine a reference range of A. fumigatus-specific IgG levels within a healthy adult Omani population. Methods: This study took place during November 2015 at the Sultan Qaboos University Hospital, Muscat, Oman. The sera of 125 healthy Omani blood donors were tested for A. fumigatusspecific IgG levels using an automated fluorescence enzyme immunoassay. Results: Initially, the data were not normally distributed; however, log transformation and the exclusion of four outliers resulted in an acceptable Gaussian distribution. The reference range was 2.0–68.7 mgA/L at the 2.5th and 97.5th percentiles, respectively, with 90% confidence intervals of 2.0–3.0 mgA/L and 48.0–76.0 mgA/L, respectively. Conclusion: The A. fumigatusspecific IgG reference range within a healthy adult Omani population was comparable to those reported in other populations.

Objectives: The presence of abnormally high levels of Aspergillus fumigatus-specific immunoglobulin (Ig) G antibodies can serve as a diagnostic criterion for severe conditions like allergic bronchopulmonary and chronic pulmonary aspergillosis. This study aimed to determine a reference range of A. ...

مادة فرعية

المؤلف : Al Rahman, Munira.

مؤلف مشارك : Al Kindi, Mahmood
Ibrahim Kutty
Al Kalbani, Ibrahim
Jalila Alshekaili

بيانات النشر : Muscat، Sultanate of Oman : Sultan Qaboos University / College of Medicine and Health Sciences، 2018مـ.

التصنيف الموضوعي : العلوم البحتة|علم الأحياء .

المواضيع : Immunology - Researchs - Sultanate of Oman.

المناعة، علم - البحوث - سلطنة عمان.

رقم الطبعة : 1

المصدر : Sultan Qaboos University / College of Medicine and Health Sciences : Muscat، Sulatante of Oman.

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