ورقة بحثية
اتجاهات ونتائج علاج سرطان الرئة ذو الخلايا غير الصغيرة في المرضى العمانيين خبرة مستشفى جامعي = Trends and Outcomes of Non-Small-Cell Lung Cancer in Omani Patients Experience at a university hospitals

Furrukh, Muhammad.


 

اتجاهات ونتائج علاج سرطان الرئة ذو الخلايا غير الصغيرة في المرضى العمانيين خبرة مستشفى جامعي = Trends and Outcomes of Non-Small-Cell Lung Cancer in Omani Patients Experience at a university hospitals

Furrukh, Muhammad.

Objectives: The incidence of lung cancer in Oman has shown a gradual but definitive increase since 2002. This study aimed to evaluate the demographic and epidemiological characteristics and survival outcomes of patients with non-small-cell lung cancer (NSCLC) at a university hospital in Oman. Methods: This study was conducted from January to June 2016. A retrospective analysis was performed of consecutive patients diagnosed with NSCLC presenting to the Sultan Qaboos University Hospital (SQUH) in Muscat, Oman, between March 2000 and December 2015. Clinical features at presentation and prognostic and predictive markers were reviewed. Kaplan-Meir estimates were used to determine relapse-free survival, progression-free survival (PFS) and overall survival (OS). Results: A total of 104 patients presented to SQUH during the study period. The median age at diagnosis was 64 years. Overall, 62 patients (59.6%) had adenocarcinomas. Only 12 patients (11.5%) presented in the early stages (I or II) of the disease and the majority of patients had an Eastern Cooperative Oncology Group performance status of 1 (27.9%) or 2 (26.0%). The prevalence of epidermal growth factor receptor mutations was 27.9%. The median PFS for patients with advanced disease (stages III or IV) was five months and the median OS for all patients was seven months. After five years, 50.0%, 60.0%, 10.0% and 8.0% of patients with disease stages I, II, III and IV, respectively, were alive. Conclusion: Patients with NSCLC in Oman were found to present at an advanced stage. However, patient outcomes were similar to those reported in the USA.

Objectives: The incidence of lung cancer in Oman has shown a gradual but definitive increase since 2002. This study aimed to evaluate the demographic and epidemiological characteristics and survival outcomes of patients with non-small-cell lung cancer (NSCLC) at a university hospital in Oman. Meth...

مادة فرعية

المؤلف : Furrukh, Muhammad.

مؤلف مشارك : Shiyam Kumar
Khawaja F. Zahid
Hanan S. Al-Shamly
Al Jabri, Zainab Ali
Ikram A. Burney
Al Moundhri, Mansour S

بيانات النشر : Muscat، Sultanate of Oman : Sultan Qaboos University / College of Medicine and Health Sciences، 2017مـ.

التصنيف الموضوعي : العلوم التطبيقية|العلوم الطبية .

المواضيع : Lung Cancer - Sultanate of Oman.

سرطان الرئة - سلطنة عمان.

رقم الطبعة : 3

المصدر : Sultan Qaboos University / College of Medicine and Health Sciences : Muscat، Sulatante of Oman.

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